Human Leukocyte Antigen (HLA) is a protein found on White blood cells. They play a vital role in defending the body against viral or bacterial infections and determine the bodys response to drugs, vaccinations, autoimmune disorders and cancers. HLA types also form the basis for acceptance/ rejection of a transplanted organ/ bone marrow.
BMSTs NABH Accredited, HLA laboratory is one of the foremost testing facilities in India which carries out pre and post- transplant tests for both Bone Marrow Transplant as well as solid organ-Kidney, heart, liver- transplants.
Clinical use: The CDC Cross Match is done to detect presence of pre-formed anti-donor HLA antibodies in the serum of potential recipients. The AHG CDC cross match detects these antibodies with greater sensitivity than the routine
Specimen required: Patient serum & donor’s ACD blood sample 20-30 ml
Clinical use: To detect the presence of antibodies directed against the HLA antigens of the donor & specific HLA IgG antibodies against Class I and/or Class II antigens. It is ideal for pre- and post-transplant testing.
Specimen required: Patient serum (from 5 mL blood sample) & donor ACD blood sample, 20-30 ml
Clinical use: To identify the Human Leukocyte antigens/ HLA alleles present on the WBCs of the donor / patient for Bone Marrow as well as solid organ transplant
Specimen required: EDTA blood sample 5 ml
Clinical use: Class I and II ID panels provide antibody identification and panel-reactive antibody (PRA) information
Specimen required: Patient serum, 5 ml
Clinical use: Immunoassays used to qualitatively detect the specificity of HLA, Class I & II IgG antibodies for optimized selection of donor for allosensitized patients especially patients waiting for deceased donor transplant
Specimen required: Patient serum (5 ml)
Clinical use: This test detects IgG antibodies to HLA Class I and Class II antigens. The presence or absence of these antibodies has a role in determining the survival of transplant allografts
Specimen required: Patient Serum collected from 4- 5 ml whole blood sample
Clinical use: Flowcytometric crossmatch is a sensitive and accurate test to detect the presence of donor-specific low titre anti-HLA antibodies. his method utilizes a multicolored approach with fluorescently labelled monoclonal antibody to discriminate T-cells from B-cells.
Specimen required: Patient serum & donor’s ACD blood sample 20-30 ml
With our expertise and experience in the field of Transplant Immunology since 1996, we offer clinical correlation & advice for transplant cases